Synthetic Studies of Ambruticin: Preparation of the C1-C8 Tetrahydropyran and the C17-C24 Dihydropyran Segments

Authors

  • Luping Liu
  • Julie Wondergem
  • William A. Donaldson Chemistry Department, Marquette University 2370 North 103rd Street P.O. Box 1881 , Milwaukee, WI 53201-1881 Wauwatosa, WI 53226 414-288-7374 FAX: 414-288-7066 414-475-0044

Abstract

The C1-C8 tetrahydropyran and the C17-C24 dihdropyran segments of ambruticin were prepared from L-arabinose in 11 steps, 7.6% overall yield and from (S)-ethyl lactate in 8 steps, 22.2% overall yield respectively.

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Published

2015-07-01

Issue

Vol. 4 No. 4 (2015)

Section

Organic Chemistry

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