Synthesis of New Organophosphorus Compounds Derived from 2- Arylidenecyclohexane-1-one

Authors

  • Mona Hizkial Arsanious Department of Organometallic and Metalloid Chemistry, National Research Center Giza, Egypt http://orcid.org/0000-0002-9362-2399
  • Ibtisam Hennawy Department of Organometallic and Organometalloid Chemistry National Research Centre, 33 El- Bahouth Street Dokki, P.O. Box 12622, Giza

Abstract

2-(4-Arylidene)cyclohexane-1-one derivatives react with 2,4- bis (phenylthio) -1,3-dithia,2,4- diphosphetane-2,4-disulphide (JR)  to give a mixture of the  benzo-dithiadiphosphi-nine -2-sulphides and dithiadispirotetradecanes. The same reaction was carried out using Lawesson's reagent to yield the 4-methoxyphenylbenzo-dithiaphosphinine sulfides. A putative reaction mechanism involves an initial thiation of arylidenecyclohexane-1-one derivatives then Michael addition by sulfide anion of Lawesson's reagents followed by intramolecular cyclization and resulting in the formation of new heterocyclic compounds containing phosphorus moiety. Biological activities for some of the new compounds are also reported. 

Author Biography

Mona Hizkial Arsanious, Department of Organometallic and Metalloid Chemistry, National Research Center Giza, Egypt

Department of Organometallic and Metalloid Chemistry, National Research Center Giza, Egypt

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Published

2016-05-14

Issue

Vol. 5 No. 4 (2016)

Section

Organic Chemistry

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