Selective synthesis of functionalized allyl amines and ethers from (E)-2,3-bisphosphonated allyl bromide

Authors

  • Maha Ameur
  • Hassen Amri Professor

Abstract

An efficient and straightforward approach toward functionalized allylic amines and ethers is disclosed starting from tetraethyl (3-bromoprop-1-ene-1,2-diyl)bisphosphonate (E)-1 and secondary and tertiary amines. The coupling reaction of allyl bromide (E)-1with less bulky secondary amines provides a new family of allylamines 3, while, its reaction with more bulky secondary and tertiary amines, in methanol at reflux, led to functional allyl ethers 4 and 5.

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Published

2016-05-20

Issue

Vol. 5 No. 4 (2016)

Section

Organic Chemistry

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