1,3-Dipolar cycloaddition of azomethine ylide from Phtaloylimidophenylalanyl-2-hydroxymethylaziridine

Authors

  • Assia Keniche Laboratory of Organic chemistry, Natural Products and Analysis (COSNA). University of Tlemcen. P.O. Box 119 Tlemcen 13000/Algeria.
  • Wassila Drici Laboratory of Organic chemistry, Natural Products and Analysis (COSNA). University of Tlemcen. P.O. Box 119 Tlemcen 13000/Algeria.
  • Mohamed Zakaria Slimani Donostia International Physics Center. SGIker-RMN San Sebastián. Spain.
  • Abdelmoumen Mezrai Laboratory of Organic chemistry, Natural Products and Analysis (COSNA). University of Tlemcen. P.O. Box 119 Tlemcen 13000/Algeria.
  • Joseph Kajima Mulengi Laboratory of Organic chemistry, Natural Products and Analysis (COSNA). University of Tlemcen. P.O. Box 119 Tlemcen 13000/Algeria.

DOI:

https://doi.org/10.13171/mjc.2.4.2013.07.09.12

Abstract

Phtaloylimidophenylalanyl-2-hydroxymethylaziridine has been used as a starting material to yield azomethine ylide through thermal opening and was then involved into 1,3-dipolar cycloaddition reactions. Different five-membered adducts were obtained and were fully identified. The latter might be considered useful starting materials for further functionalization to provide novel compounds of biological interest.

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Published

2013-09-07

Issue

Vol. 2 No. 4 (2013)

Section

Organic Chemistry

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