Chemical Composition, Antioxidant and Anti-acetylcholinesterase activities of Tunisian Crithmum maritimum L. Essential oils

Authors

  • Asma Nguir Laboratoire de chimie Hétérocyclique, Produits Naturels et Réactivité. Equipe : Chimie Bio-organique et Produits Naturels, Département de Chimie, Faculté des Sciences de Monastir, Université de Monastir, Avenue de l’Environnement, 5019 Monastir Tunisie
  • Malek Besbes Laboratoire des maladies transmissibles et des substances biologiquement actives Faculté de Pharmacie, 5019 Monastir, Tunisie
  • Hichem Ben Jannet Laboratoire de chimie Hétérocyclique, Produits Naturels et Réactivité. Equipe : Chimie Bio-organique et Produits Naturels, Département de Chimie, Faculté des Sciences de Monastir, Université de Monastir, Avenue de l’Environnement, 5019 Monastir Tunisie
  • Guido Flamini Dipartimento di Scienze Farmaceutiche sede chimica Bioorganica e Biofarmacia Via Bonanno 33, 56126 Pisa, Italy
  • Fethia Harzallah-Skhiri Institut supérieur de biotechnologie de Monastir, Université de Monastir, 5000, Monastir, TUNISIE.
  • M’hamed Ali Hamza Laboratoire de chimie Hétérocyclique, Produits Naturels et Réactivité. Equipe : Chimie Bio-organique et Produits Naturels, Département de Chimie, Faculté des Sciences de Monastir, Université de Monastir, Avenue de l’Environnement, 5019 Monastir Tunisie

DOI:

https://doi.org/10.13171/mjc.1.4.2011.03.12.23

Abstract

 acetylcholinesterase properties of the aerial parts and roots essential oils from Crithmum maritimum L., Apiaceae, gathered in the area of Monastir (Tunisia). The essential oils have been analysed by GC and GC-MS. Remarkable differences were found between the constituent percentages of the different studied organs. The most important compounds from the aerial parts were: γ-terpinene (39.3%), methylcarvacrol (21.6%) and p-cymene (11.8%). In the roots oil, the main components were terpinolene (36.9%), dillapiole (26.8%) and γ-terpinene (21.9%). The antioxidant activity of the two oils was evaluated by employing 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging tests. The results showed that the antioxidant capacity assessed by different in vitro tests were moderate, the ABTS assay after 20 min (IC50 = 0.051 mg/mL) of aerial parts and (IC50 = 0.643 mg/mL) of the roots, appeared to be more potent than that for the DPPH assay (IC50 = 0.92 mg/mL) of aerial parts and (IC50 = 0.048 mg/mL) of roots. In addition, the examined oils showed the highest AchE inhibitory 1 mg/mL activity (31.16% and 26.35%, for the aerial parts and roots, respectively).

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Published

2011-12-03

Issue

Vol. 1 No. 4 (2011)

Section

Phytochemistry

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